Ultimate Spider-Man #20 (2002)

Justin Hammer flees the press conference, but Doctor Octopus attacks to keep him there. Spider-Man steps in, protecting the crowd and holding Doc Ock's assault back in full view of the press. After striking and pantsing him, Spider-Man subdues him and removes his arms. Just as he calms down to take a breather, Kraven the Hunter arrives to have it out in combat.